AKI: fluid overload and mortality

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Fluid Overload

Despite its high prevalence and significant rates of associated morbidity and mortality, the syndrome of decompensated heart failure (HF) remains poorly defined and vastly understudied. HF is due to several mechanisms including pump dysfunction disorder, neurohormonal activation disorder, and salt-water retention disorder. The first step of the syndrome includes cardiac damage and remodeling in...

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Oliguria and fluid overload.

Oliguria is a very common clinical situation that is also often difficult to interpret since it may represent either the expression of a disease or an appropriate response of the kidneys to extracellular volume depletion or decreased renal blood flow. In patients with acute kidney injury, oliguria is independently associated with mortality. Fluid overload is a complication of the impaired sodiu...

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AKI and Long-Term Risk for Cardiovascular Events and Mortality.

AKI associates with increased long-term risk of mortality, but the prognostic significance of AKI in terms of long-term cardiovascular disease remains unconfirmed. We conducted a systematic review and meta-analysis to assess whether AKI associates with long-term cardiovascular disease. We included cohort studies that examined adults with and without AKI and reported a multivariable-adjusted rel...

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Fluid Overload Is Associated With Higher Mortality and Morbidity in Pediatric Patients Undergoing Cardiac Surgery.

OBJECTIVES Fluid overload after pediatric cardiac surgery is common and has been shown to increase both mortality and morbidity. This study explores the risk factors of early postoperative fluid overload and its relationship with adverse outcomes. DESIGN Secondary analysis of the prospectively collected data of children undergoing open-heart surgery between 2004 and 2008. SETTING Tertiary n...

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How to avoid fluid overload.

PURPOSE OF REVIEW This review highlights the recent evidence describing the outcomes associated with fluid overload in critically ill patients and provides an overview of fluid management strategies aimed at preventing fluid overload during the resuscitation of patients with shock. RECENT FINDINGS Fluid overload is a common complication of fluid resuscitation and is associated with increased ...

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ژورنال

عنوان ژورنال: Nature Reviews Nephrology

سال: 2009

ISSN: 1759-5061,1759-507X

DOI: 10.1038/nrneph.2009.138